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Senior R&D Scientific Systems and Software Engineer

Frontier Medicines


Frontier Medicines, located in South San Francisco, CA, is a pre-clinical stage biopharmaceutical company that is pioneering breakthrough technologies to drug the “undruggable” proteome.  Frontier Medicines’ proprietary platform uses chemoproteomics – an innovative approach to chemically interrogate proteins in living systems – to discover and pharmacologically target new binding pockets (or hotspots) on proteins for the purpose of making them accessible to therapeutic intervention.

We are a data driven research company with a unique chemoproteomics platform at its core. Our platform generates massive amounts of data and we have established a cloud-based and on-premise state of the art high performance computing environment. This infrastructure enables flawless execution of data workflows, algorithms, visualization and onboarding of our ever-growing proprietary internal data. We are continuously developing new methods needing customized data handling and are striving to further improve our end to end data pipeline and applications.

Frontier Medicines is seeking a multi-talented individual to develop data solutions for key activities at Frontier enabling quick decision making. This can include tools and pipelines for data engineering and storage as well as analysis workflows and end user tool developments for insight dissemination and data visualization. The successful candidate, as a senior IT professional in the company, will have the opportunity to participate and lead in strategic discussions about the future design and investments in the area of data, cloud-based solutions as well as influencing the design and layout of Frontier’s on-premise infrastructure.

Our machine learning algorithms are central to everything we do at Frontier and hence the successful candidate will play an important role as a key team member with data scientists and research scientists to harness the full potential from our unique data allowing us to reshape small molecule drug discovery.

This role is key to Frontier Medicine’s success and an opportunity to join and work in a highly collaborative and energetic team in a startup environment with short communication lines across functions and departments. This position and is located in South San Francisco and will report directly to the CTO.

Key responsibilities:

  • Development, design, customization, implementation and on-going support of scientific computing environment, workflows and licensed informatics applications.
  • Design, development and implementation of web based applications and security protocols.
  • Key liaison to external IT resources managing Frontier’s cloud infrastructure and corporate IT
  • Design and implement data workflows powering our discovery engines.
  • Serve as a strategic and hands-on individual contributor resource.




  • BS with >7 or MS/PhD with >4 years professional experience in Information Technology, Computer Science, Software Engineering
  • Knowledge of Linux, shell scripting, and programming (e.g., Python, Java, SQL).
  • Experience with database design, software development, and solutions as data services to enable interoperability and delivery to end-users.
  • Up to date with technology trends, interested to learn and develop in innovative new data solutions and applications.
  • Working knowledge in cloud-based environments, AWS experience is a plus
  • Ability to work with independence and drive in a startup environment.
  • Legally authorized to work in the US.




Location: South San Francisco


Post Date: 8/20/2020 12:00:00 AM
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